Willard is playing Jeff City Helias, Rogersville hosting Marshall.
Meanwhile two other teams have punched their tickets to the Final Four.
In Class 1, Norwood will play Sturgeon in one semifinal.
In Class 2, Clever will play South Callaway in a semifinal as well.
This is second straight year that the Bluejays have made it to Meador Park and the state Final Four.
A year ago Clever finished third, and they worked hard to get back.
"They've done an excellent job the whole year," said Clever coach Justin Snider. "They've worked their tails off every day starting from the fall on. From day one this was our goal. They've done everything that they needed to to get back. They work hard and execute.."
"They shouldn't let the big field and the atmosphere, there will be a lot of fans and a lot of cheering they can't let it get to them," said Clever senior David Pennewell. "Last year we kind of did that and we got real tense. Not loose enough to win the game. That's not going to happen this year."